NIH-funded research U01 cooperative agreement

Using AI to improve glaucoma screening in community health centers

Official title: RFA-DP-24-081 Implementing AI-based Glaucoma Screening within Federally Qualified Health Centers

Funded at University of Alabama at Birmingham · NIH-11023851 · Data updated 2026-11-12

This study is testing a new way to use artificial intelligence to help find glaucoma earlier in people who might not have easy access to eye care, especially in communities with a lot of Black residents, where glaucoma is more common.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Alabama at Birmingham
NIH-funded
Lab location1 site (Birmingham, United States)
Project startSeptember 30, 2024
Project endSeptember 29, 2029
Funding year2024
Award (this year)$750,000
NIH project number1U01DP006827-01
Project IDNIH-11023851 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals living in medically underserved areas, particularly those at higher risk for glaucoma, such as Black patients.

Less likely to help

Patients who do not reside in areas served by Federally Qualified Health Centers or who are not at risk for glaucoma may not benefit from this research.

What this research studies

This research investigates a new approach to screening for primary open angle glaucoma (POAG) using artificial intelligence within Federally Qualified Health Centers (FQHCs). The study aims to implement a validated AI algorithm that interprets ocular imaging and clinical data to enhance early detection of glaucoma, particularly in underserved populations. By focusing on areas with high Black populations, where the prevalence of POAG is significantly higher, the research seeks to provide accessible and effective eye care. The program will be evaluated for its feasibility and effectiveness in improving screening rates and outcomes for at-risk patients.

Why it matters

Potential benefit: If successful, this research could lead to earlier detection and treatment of glaucoma, significantly improving eye health outcomes for millions of individuals.

How similar studies have gone: Previous research has shown success in using AI for glaucoma detection, indicating a promising approach for this implementation study.

Where this research is happening

  • University of Alabama at Birmingham
    Birmingham, United States
    Active

Researchers

  • Principal investigator: Owsley, Cynthia — University of Alabama at Birmingham
  • Study coordinator: Owsley, Cynthia

Related research

Other NIH-funded projects on the same topics.

  • IOP and CSF Pressure in Glaucoma Risk

    This grant studies how eye pressure and cerebrospinal fluid pressure together influence glaucoma risk and vision loss.

    NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11644421

  • Comparing tube positions in glaucoma implants to protect corneal cells

    This trial compares two tube placements for glaucoma drainage implants to see which better protects corneal cells and controls eye pressure in people with uncontrolled glaucoma.

    NIH research University of California, San Francisco · San Francisco, United States · NIH-11520347

  • Automated topographic test for glaucoma detection and progression

    A new automated method uses topographic structure-function mapping to help diagnose glaucoma earlier and track its progression in patients.

    NIH research Columbia University Health Sciences · New York, United States · NIH-11516608

  • Using AI on eye scans and genes to predict glaucoma risk

    This project uses artificial intelligence on eye scans, vision tests, and genetic information to find people most likely to develop or have worsening glaucoma.

    NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11469603

  • AI-based glaucoma screening in community health centers

    A new, easy-to-use AI screening approach will be tested in federally funded health centers to help identify people at risk for glaucoma, especially in communities with higher risk.

    NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11454104

  • Understanding how glaucoma genes control eye cell function

    A long-term research project will study how genetic factors affect eye cells in adults with glaucoma to uncover new ideas for protecting vision.

    NIH research Massachusetts Eye and Ear Infirmary · Boston, United States · NIH-11450761

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.