Using AI to find new treatments for substance use disorders
Official title: AI Platform to Discover Therapeutics for Substance Use Disorders
Funded at Callentis Consulting Group LLC · NIH-11144833 · Data updated 2026-11-12
This study is exploring how artificial intelligence can help find new treatments for substance use disorders by looking at specific pathways in the body that might help reduce cravings for things like opioids, nicotine, and alcohol, so that patients can have better options for recovery.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Callentis Consulting Group LLC NIH-funded |
| Lab location | 1 site (Austin, United States) |
| Project start | May 1, 2025 |
| Project end | April 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $397,829 |
| NIH project number | 1R41DA062993-01 |
| Project ID | NIH-11144833 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from substance use disorders, including those addicted to alcohol, nicotine, or opioids.
✕Less likely to help
Patients who do not have substance use disorders or those who are not seeking treatment for addiction may not benefit from this research.
What this research studies
This research aims to tackle substance use disorders (SUDs) by utilizing artificial intelligence (AI) to identify and validate potential treatment targets. The approach involves creating curated datasets and machine learning models to accelerate drug discovery processes. By focusing on the glucagon-like peptide 1 (GLP-1) pathways, the research seeks to understand how these pathways can reduce cravings for addictive substances like opiates, nicotine, and alcohol. Patients may benefit from new therapeutic options that emerge from this innovative AI-driven methodology.
Why it matters
Potential benefit: If successful, this research could lead to the development of effective new treatments for individuals struggling with substance use disorders.
How similar studies have gone: Other research has shown promise in using AI for drug discovery, particularly in targeting complex conditions like addiction, suggesting that this approach could yield significant advancements.
Where this research is happening
-
Callentis Consulting Group LLC
Austin, United States Active
Researchers
- Principal investigator: Lauver, Dale Adam — Callentis Consulting Group LLC
- Study coordinator: Lauver, Dale Adam
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.