Using AI to classify breast cancer cell types based on organelle structure
IMAT-ITCR Collaboration: Artificial intelligence enhanced breast cancer dormancy cell classification-based organelle-morphology and topology
This study is looking at how using artificial intelligence can help doctors better understand different types of breast cancer cells by examining their shapes and how their parts are arranged, which could lead to more personalized treatment options for patients.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albany Medical College NIH-funded |
| Lab location | 1 site (Albany, United States) |
| Project ID | NIH-10884759 on NIH RePORTER |
What this research studies
This research investigates how artificial intelligence can enhance the classification of breast cancer cells by analyzing the morphology and spatial relationships of organelles within the cells. By developing a novel pipeline that quantifies organelle topology, the study aims to identify distinct subpopulations of cancer cells that may be involved in metastatic progression. Patients' tumor samples will be analyzed using advanced machine learning techniques to improve the understanding of tumor heterogeneity and potentially guide treatment decisions.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with breast cancer who are undergoing treatment or have tumor samples available for analysis.
Not a fit: Patients with non-breast cancer malignancies or those without available tumor samples may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate classifications of breast cancer, enabling personalized treatment strategies that target specific cancer cell subpopulations.
How similar studies have performed: While the use of AI in cancer classification is an emerging field, this specific approach focusing on organelle topology is relatively novel and has not been extensively tested in prior studies.
Where this research is happening
Albany, United States
- Albany Medical College — Albany, United States (Active)
Researchers
- Principal investigator: Barroso, Margarida — Albany Medical College
- Study coordinator: Barroso, Margarida
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.