NIH-funded research R01 grant

Using AI to analyze kidney ultrasound images for fibrosis assessment

Official title: Development and Validation of a Deep Learning system to estimate Interstitial Fibrosis from a kidney ultrasonography image

Funded at University of California, San Diego · NIH-10932906 · Data updated 2026-11-12

This study is testing a new AI tool that looks at kidney ultrasound images to help doctors find and understand kidney damage without needing to do a painful biopsy, making it easier for patients to keep track of their kidney health.

More Fibrosis research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego
NIH-funded
Lab location1 site (La Jolla, United States)
Project startSeptember 22, 2023
Project endJuly 31, 2028
Funding year2024
Award (this year)$313,396
NIH project number5R01DK138395-02
Project IDNIH-10932906 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals with chronic kidney disease or those at risk of kidney fibrosis.

Less likely to help

Patients with acute kidney conditions or those who do not undergo kidney ultrasound imaging may not benefit from this research.

What this research studies

This research aims to develop a deep learning system that can analyze kidney ultrasound images to estimate the presence and severity of interstitial fibrosis, a condition that can lead to kidney function decline. Currently, interstitial fibrosis is often undetected due to reliance on invasive kidney biopsies and traditional biomarkers. By utilizing artificial intelligence, this project seeks to create a non-invasive method that can provide valuable insights into kidney health over time. The study will validate this AI system against the gold standard of kidney biopsy results.

Why it matters

Potential benefit: If successful, this research could provide a non-invasive tool for early detection and monitoring of kidney fibrosis, potentially improving patient outcomes.

How similar studies have gone: Other research has shown promise in using AI for medical imaging analysis, indicating potential success for this novel approach.

Where this research is happening

  • University of California, San Diego
    La Jolla, United States
    Active

Researchers

  • Principal investigator: Athavale, Ambarish — University of California, San Diego
  • Study coordinator: Athavale, Ambarish

Related research

Other NIH-funded projects on the same topics.

  • Deep learning to estimate kidney scarring from ultrasound

    A new AI-based tool uses ultrasound images to estimate kidney scarring (interstitial fibrosis) without needing a biopsy, helping people with chronic kidney disease and their doctors track disease.

    NIH research University of California, San Diego · La Jolla, United States · NIH-11374958

  • Using AI with kidney ultrasound to find scarring

    This project is creating an artificial intelligence tool that uses routine kidney ultrasound pictures to find and measure scarring in the kidneys for people with chronic kidney disease.

    NIH research University of California, San Diego · La Jolla, United States · NIH-11143702

  • Understanding heart fibrosis with AI, MRI, and genomics

    A doctor-scientist is using artificial intelligence, advanced heart MRI, and genetic data to learn how scar tissue forms in the aging heart and how to prevent it.

    NIH research Brigham and Women's Hospital · Boston, United States · NIH-11381731

  • Predicting Post-Covid Lung Scarring with Easy-to-Understand Deep Learning and Key Biomarkers

    Aims to use explainable artificial intelligence and biomarker data from multiple hospitals to predict which patients will develop long-term lung scarring after COVID-19.

    NIH research Northwestern University · Chicago, United States · NIH-11380916

  • Early prediction of lung scarring after COVID using explainable AI

    This project uses explainable AI on CT scans and medical records to find people at risk of lung scarring after COVID-19.

    NIH research Northwestern University · Chicago, United States · NIH-11178702

  • Measuring liver scarring using MRI and advanced computer techniques

    This study is looking for a gentle way to check for liver scarring in people with chronic liver disease using advanced MRI technology and smart computer programs, so you won’t need any painful biopsies.

    NIH research Cincinnati Childrens Hosp Med Ctr · Cincinnati, United States · NIH-10769797

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.