NIH-funded research NIH-funded research

Using AI and advanced imaging to improve colorectal cancer prevention.

Official title: BCCMA: VA Colorectal Cancer Clinical & Computational Collaborative (VA-5C): Project #2 - Artificial Intelligence and Multispectral Imaging of Colorectal Polyps.

Funded at VA Boston Health Care System · NIH-10918837 · Data updated 2026-11-12

This study is working on a smart tool that helps doctors spot and check for polyps during colonoscopies in veterans, making it easier to prevent colorectal cancer and reducing the need for extra tests.

More Colorectal Cancer research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVA Boston Health Care System
NIH-funded
Lab location1 site (Boston, United States)
Project startOctober 1, 2024
Project endSeptember 30, 2028
Funding year2025
NIH project number1I01CX002733-01A1
Project IDNIH-10918837 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are veterans undergoing colonoscopy who may have colorectal polyps.

Less likely to help

Patients who do not have colorectal polyps or are not veterans may not benefit from this research.

What this research studies

This research aims to enhance the prevention of colorectal cancer (CRC) in veterans by developing an artificial intelligence (AI)-based platform that provides real-time histology assessments during colonoscopy. By utilizing multispectral imaging, the project seeks to accurately identify and assess colorectal polyps, reducing unnecessary biopsies and associated costs. The goal is to create a widely adoptable tool that improves the efficiency and accuracy of polyp management, ultimately leading to better patient outcomes. This collaborative effort involves multiple VA centers and focuses on CRC precursors as key targets for intervention.

Why it matters

Potential benefit: If successful, this research could significantly improve the accuracy of polyp assessments during colonoscopy, leading to better prevention strategies for colorectal cancer.

How similar studies have gone: Other research has shown promise in using AI for medical imaging, indicating potential success for this novel approach in colorectal cancer prevention.

Where this research is happening

  • VA Boston Health Care System
    Boston, United States
    Active

Researchers

  • Principal investigator: Singh, Satish K — VA Boston Health Care System
  • Study coordinator: Singh, Satish K

Related research

Other NIH-funded projects on the same topics.

  • Improving colorectal cancer screening and follow-up care.

    This study is working to help more people get screened for colorectal cancer and receive the follow-up care they need, especially those who haven't been screened much before, so that everyone can have better access to important health checks and improve their overall health.

    NIH research Research Triangle Institute · Research Triangle Park, United States · NIH-9627071

  • Colorectal cancer prognosis through a broad, collaborative study

    A large, multi-center study follows people newly diagnosed with colorectal cancer to find biomarkers and patterns that predict outcomes and guide future care.

    NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11590756

  • Ceramides and how they affect metabolism and colorectal cancer in adults

    A study in adults with obesity-related health issues will explore how a fat-related molecule called ceramide influences metabolic problems and colorectal cancer risk.

    NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11535283

  • Automated point-of-care DNA methylation test for colorectal cancer in LMICs

    A fast, affordable blood test using DNA markers to help identify people at higher risk of colorectal cancer in low- and middle-income countries.

    NIH research Johns Hopkins University · Baltimore, United States · NIH-11531863

  • Rewiring Colorectal Cancer to Harness Therapeutic Hyperactivation

    A Yale team is exploring brain-storming new ways to treat colorectal cancer by safely boosting certain cancer signaling pathways to kill cancer cells and by reshaping cancer cell states to improve responses to existing therapies.

    NIH research Yale University · New Haven, United States · NIH-11505210

  • Comparative modeling to guide colorectal cancer screening and care

    A researcher team will use computer models to study how access to care, risk, and new screening options affect colorectal cancer outcomes and costs for adults in the US.

    NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11495363

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.