Using advanced technology to predict where seizures start in epilepsy patients
Investigation of Stereotyped High-Frequency Oscillations with Computational Intelligence for the Prediction of Seizure Onset Zone in Epilepsy
This study is looking to help people with hard-to-treat epilepsy by finding out where their seizures start in the brain more accurately, using special brain recordings to spot unique patterns that could make surgery safer and more effective.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-10983614 on NIH RePORTER |
What this research studies
This research focuses on improving the accuracy of locating the seizure onset zone (SOZ) in patients with refractory epilepsy. By analyzing intracranial EEG (iEEG) recordings, the study aims to identify specific high-frequency oscillation (HFO) patterns that are unique to the SOZ. The approach utilizes advanced computational techniques to differentiate between pathological and physiological HFOs, potentially reducing the need for prolonged monitoring in the epilepsy monitoring unit. This could lead to safer and more effective surgical interventions for epilepsy patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with refractory epilepsy who are being considered for surgical intervention.
Not a fit: Patients with well-controlled epilepsy or those not eligible for surgical treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly enhance the precision of surgical planning for epilepsy patients, leading to better outcomes and reduced risks associated with current monitoring methods.
How similar studies have performed: Other research has shown promise in using advanced computational methods to analyze EEG data, suggesting that this approach could lead to significant advancements in epilepsy treatment.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Ince, Nuri Firat — Mayo Clinic Rochester
- Study coordinator: Ince, Nuri Firat
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.