Using advanced technology to improve epilepsy surgery for children
Refining neurophysiological biomarkers of epilepsy using deep learning to guide pediatric epilepsy surgery
This study is looking at ways to help kids with epilepsy who don't respond to medication by using special brain scans to find the exact spots causing their seizures, so doctors can perform safer and more effective surgeries.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-11065462 on NIH RePORTER |
What this research studies
This research focuses on children with medication-resistant focal epilepsy, aiming to enhance surgical outcomes by identifying specific brain biomarkers. The approach integrates advanced electroencephalogram (EEG) analysis with deep learning techniques to analyze high-frequency oscillations (HFOs) in the brain. By distinguishing between harmful and normal brain activity, the research seeks to accurately locate the areas responsible for seizures while preserving critical brain functions. This innovative methodology could lead to more effective surgical interventions for young patients suffering from epilepsy.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who have medication-resistant focal epilepsy and may be considered for surgical intervention.
Not a fit: Patients who do not have epilepsy or those whose condition is well-managed with medication may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve surgical outcomes for children with epilepsy, potentially leading to seizure freedom and better quality of life.
How similar studies have performed: Previous research has shown promise in using advanced EEG analysis and machine learning techniques to improve outcomes in epilepsy treatment, indicating that this approach could be effective.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Nariai, Hiroki — University of California Los Angeles
- Study coordinator: Nariai, Hiroki
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.