Using advanced technology to improve deep brain stimulation for depression treatment
Multimodal Biometrics to Optimize and Scale Decision Support for Depression DBS
['FUNDING_OTHER'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-11050434
This study is looking at how to make deep brain stimulation (DBS) work better for people with severe depression that hasn't improved with other treatments by using a new tool to personalize the therapy based on how each person responds.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11050434 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing deep brain stimulation (DBS) for patients with treatment-resistant depression (TRD) by developing a new biomarker that helps tailor treatment. The approach combines various brain imaging techniques to monitor and adjust DBS therapy based on individual patient responses. By integrating this biomarker into clinical decision-making, the goal is to optimize the effectiveness of DBS and improve long-term outcomes for patients suffering from severe depression. This innovative method aims to make DBS a more reliable and personalized treatment option.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with treatment-resistant depression who have not responded to conventional therapies.
Not a fit: Patients with mild depression or those who have not yet tried standard antidepressant treatments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options for patients with treatment-resistant depression.
How similar studies have performed: Previous research has shown promising results with deep brain stimulation for depression, but this specific approach integrating biomarkers is relatively novel.
Where this research is happening
NEW YORK, UNITED STATES
- ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MAYBERG, HELEN S — ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- Study coordinator: MAYBERG, HELEN S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.