Using advanced techniques to predict liver complications in veterans after hepatitis C treatment
Applying an 'omics' approach to predict hepatic decompensation events and hepatocellular carcinoma in veterans after HCV cure with direct acting antiviral therapy
This study is looking at how certain substances in the blood can help predict the risk of liver problems and cancer in veterans who have been treated for hepatitis C, so we can better support those who might be at higher risk after their treatment.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Durham VA Medical Center NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10980534 on NIH RePORTER |
What this research studies
This research investigates how specific metabolites can predict the risk of liver complications and cancer in veterans who have been cured of hepatitis C. By analyzing blood samples from veterans, the study aims to identify biomarkers that indicate which patients are at higher risk for severe liver issues after treatment. The approach focuses on veterans with a history of liver disease and other health conditions, ensuring that the findings are relevant to this population. If successful, this research could lead to better monitoring and preventive strategies for at-risk veterans.
Who could benefit from this research
Good fit: Ideal candidates for this research are veterans who have been cured of hepatitis C but have a history of severe liver fibrosis or other comorbidities.
Not a fit: Patients who do not have a history of hepatitis C or severe liver disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide veterans with personalized risk assessments for liver complications, leading to timely interventions and improved health outcomes.
How similar studies have performed: Previous research has shown promise in using biomarkers to predict liver-related complications in similar patient populations, indicating that this approach may be effective.
Where this research is happening
Durham, United States
- Durham VA Medical Center — Durham, United States (Active)
Researchers
- Principal investigator: Naggie, Susanna — Durham VA Medical Center
- Study coordinator: Naggie, Susanna
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.