Using advanced techniques to improve understanding and treatment of pediatric sepsis
Leveraging multi-omics to maximize the scientific value of pediatric sepsis biorepository and advance patient endotyping
['FUNDING_R21'] · CINCINNATI CHILDRENS HOSP MED CTR · NIH-10898803
This study is looking at how sepsis affects children and aims to find out which kids might respond best to certain treatments, using special biological data to improve their care.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CINCINNATI CHILDRENS HOSP MED CTR (nih funded) |
| Locations | 1 site (CINCINNATI, UNITED STATES) |
| Trial ID | NIH-10898803 on ClinicalTrials.gov |
What this research studies
This research focuses on pediatric sepsis, a critical condition that affects children and can lead to severe health complications. By utilizing multi-omics approaches, which analyze various biological data layers, the project aims to enhance the understanding of how sepsis affects children differently. The goal is to identify specific patient subgroups that may respond better to targeted therapies, ultimately improving treatment outcomes. The research will leverage existing biorepositories of biospecimens from critically ill children to uncover important biological pathways involved in sepsis.
Who could benefit from this research
Good fit: Ideal candidates for this research are critically ill children aged 0-11 years who are diagnosed with sepsis.
Not a fit: Patients who are not critically ill or do not have a diagnosis of sepsis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective, personalized treatments for children suffering from sepsis.
How similar studies have performed: Previous research using multi-omics approaches has shown promise in other areas of pediatric medicine, suggesting potential for success in this novel application.
Where this research is happening
CINCINNATI, UNITED STATES
- CINCINNATI CHILDRENS HOSP MED CTR — CINCINNATI, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ATREYA, MIHIR R — CINCINNATI CHILDRENS HOSP MED CTR
- Study coordinator: ATREYA, MIHIR R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers