Using advanced techniques to improve tissue grafts for facial reconstruction
Leveraging Microsurgery and Bioprinting for Rapidly Oriented Vascularized Tissue Engineering
['FUNDING_R01'] · PENNSYLVANIA STATE UNIVERSITY, THE · NIH-11218208
This study is exploring new ways to help people heal better after surgery for facial injuries by using tiny needles and 3D printing to create grafts that connect more effectively with blood vessels, making recovery faster and easier.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | PENNSYLVANIA STATE UNIVERSITY, THE (nih funded) |
| Locations | 1 site (UNIVERSITY PARK, UNITED STATES) |
| Trial ID | NIH-11218208 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing reconstructive surgery for craniomaxillofacial injuries by developing new methods to improve the vascularization of tissue-engineered grafts. The approach combines microsurgery techniques, specifically vascular micropuncture, with cutting-edge 3D printing technology to create better blood vessel integration in grafts. By using a fine needle to create small perforations in blood vessels, the research aims to promote faster healing and integration of the grafts into the body. This innovative method seeks to overcome current limitations in reconstructive surgery and improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from craniomaxillofacial injuries requiring reconstructive surgery.
Not a fit: Patients with conditions unrelated to craniomaxillofacial injuries or those who do not require surgical intervention may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and reliable reconstructive surgeries, resulting in better functional and cosmetic outcomes for patients.
How similar studies have performed: Previous research has shown promise in using similar microsurgical and tissue engineering techniques, indicating potential for success in this novel approach.
Where this research is happening
UNIVERSITY PARK, UNITED STATES
- PENNSYLVANIA STATE UNIVERSITY, THE — UNIVERSITY PARK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: OZBOLAT, IBRAHIM — PENNSYLVANIA STATE UNIVERSITY, THE
- Study coordinator: OZBOLAT, IBRAHIM
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.