Using advanced MRI to visualize oxidative stress in the body
Visualizing oxidative stress using hyperpolarized magnetic resonance
This study is exploring a new way to see how oxidative stress affects your body using a special type of MRI and vitamin C, which could help us better understand diseases like cancer and how they progress.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10842444 on NIH RePORTER |
What this research studies
This research focuses on developing a new method to visualize oxidative stress in the body using hyperpolarized magnetic resonance imaging (MRI). By utilizing a special form of vitamin C, researchers aim to non-invasively measure oxidative stress levels, which are linked to various diseases, including cancer. The approach combines advanced imaging techniques with the body's natural metabolic processes to provide real-time insights into cellular health. This innovative method could significantly improve our understanding of how oxidative stress affects disease progression and treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to oxidative stress, such as cancer or neurodegenerative diseases.
Not a fit: Patients who do not have conditions associated with oxidative stress or those who are not undergoing treatment for such conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools for assessing oxidative stress and improving treatment strategies for conditions like cancer.
How similar studies have performed: This approach is innovative and has not been widely tested in clinical settings, although similar imaging techniques have shown promise in other areas of medical research.
Where this research is happening
New York, United States
- Sloan-Kettering Inst Can Research — New York, United States (Active)
Researchers
- Principal investigator: Keshari, Kayvan R — Sloan-Kettering Inst Can Research
- Study coordinator: Keshari, Kayvan R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.