Using advanced MRI to understand blood flow's role in Alzheimer's disease
Non-Invasive Imaging Markers to Elicit the Role of Vascular Involvement in Alzheimer’s Disease
This study is looking at how blood flow affects Alzheimer's disease to find early signs and causes that could help improve treatments, and it's designed for people who are at risk for Alzheimer's.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-11020987 on NIH RePORTER |
What this research studies
This research investigates the relationship between blood flow and Alzheimer's disease using advanced non-invasive MRI techniques. By focusing on cerebrovascular involvement, the study aims to identify early markers and causative factors of Alzheimer's that could lead to better treatment options. The approach involves longitudinal studies of populations at risk for Alzheimer's, utilizing innovative imaging methods that provide more detailed insights into vascular dynamics than current techniques. This could help in understanding how cardiovascular health impacts Alzheimer's pathology.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for Alzheimer's disease, particularly those with mild cognitive impairment or cardiovascular issues.
Not a fit: Patients with advanced Alzheimer's disease or those without any risk factors for the condition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection of Alzheimer's disease and improved treatment strategies.
How similar studies have performed: Other research has shown promise in using advanced imaging techniques to explore vascular contributions to Alzheimer's, indicating a growing field of inquiry.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Johnson, Kevin Michael — University of Wisconsin-Madison
- Study coordinator: Johnson, Kevin Michael
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.