NIH-funded research R01 grant

Using advanced MRI to track breast cancer treatment response

Official title: Multinuclear MRI to Monitor Breast Cancer Therapy

Funded at New York University School of Medicine · NIH-10985009 · Data updated 2026-11-12

This study is looking at a new kind of MRI to help doctors see how well breast cancer treatment is working, especially for patients getting chemotherapy before surgery, so they can make better decisions about their care.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNew York University School of Medicine
NIH-funded
Lab location1 site (New York, United States)
Project startDecember 1, 2022
Project endNovember 30, 2027
Funding year2025
Award (this year)$702,400
NIH project number5R01CA266345-03
Project IDNIH-10985009 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are patients with locally advanced invasive breast cancer who are undergoing neoadjuvant chemotherapy.

Less likely to help

Patients who are not undergoing neoadjuvant chemotherapy or those with early-stage breast cancer may not benefit from this research.

What this research studies

This research focuses on improving the monitoring of breast cancer treatment by using a new type of MRI called multinuclear MRI. It aims to identify patients who are not responding well to neoadjuvant chemotherapy, which is often used to shrink tumors before surgery. By measuring changes in cellular conditions, such as sodium levels and cell volume, the study seeks to provide earlier and more accurate assessments of treatment effectiveness. This could help doctors tailor therapies more effectively for individual patients.

Why it matters

Potential benefit: If successful, this research could lead to more personalized and effective treatment plans for breast cancer patients, reducing unnecessary side effects from ineffective therapies.

How similar studies have gone: Other research has shown promise in using advanced imaging techniques to monitor cancer treatment, suggesting that this approach could be effective.

Where this research is happening

  • New York University School of Medicine
    New York, United States
    Active

Researchers

  • Principal investigator: Madelin, Guillaume — New York University School of Medicine
  • Study coordinator: Madelin, Guillaume

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.