Using advanced MRI to predict stroke risk from unstable carotid plaques
Quantitative Susceptibility Mapping for Stroke Risk Prediction of Vulnerable Carotid Plaques
This study is looking at a new MRI technique to better predict stroke risk by spotting unstable plaques in the carotid arteries, which could help doctors make smarter treatment choices for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11064793 on NIH RePORTER |
What this research studies
This research aims to improve the prediction of stroke risk by using a specialized MRI technique called quantitative susceptibility mapping (QSM) to identify unstable carotid plaques. Current methods rely on measuring the degree of carotid artery narrowing, which can lead to misclassification of patients at risk. By examining additional features of these plaques, such as intraplaque hemorrhage and calcification, the study seeks to provide a more accurate risk assessment for patients. This noninvasive approach could help guide treatment decisions, such as whether to perform carotid revascularization procedures.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with carotid artery disease who may have unstable plaques and are at risk for stroke.
Not a fit: Patients with stable carotid plaques or those who do not have carotid artery disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate identification of patients at high risk for stroke, allowing for timely and appropriate interventions.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for stroke risk assessment, indicating that this approach may be effective.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Nguyen, Thanh D — Weill Medical Coll of Cornell Univ
- Study coordinator: Nguyen, Thanh D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.