Using advanced MRI to predict outcomes of deep brain stimulation in Parkinson's disease
MULTIMODAL MRI TO PREDICT DBS MOTOR AND COGNITIVE OUTCOMES IN PARKINSON’S DISEASE
This study is looking at how special MRI scans can help doctors figure out which people with Parkinson's disease are most likely to benefit from deep brain stimulation, so they can get better relief from their symptoms and avoid unwanted side effects.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10900598 on NIH RePORTER |
What this research studies
This research investigates how advanced MRI techniques can be used to predict the effectiveness of deep brain stimulation (DBS) for patients with Parkinson's disease. By analyzing brain connectivity and other imaging data, the study aims to identify which patients are most likely to benefit from DBS, particularly in terms of motor symptom relief and cognitive side effects. The approach seeks to improve the accuracy of candidate selection for DBS, ultimately leading to better patient outcomes. Participants will undergo MRI scans to gather data that will help refine predictive models for DBS efficacy.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with Parkinson's disease who are considering deep brain stimulation as a treatment option.
Not a fit: Patients who are not diagnosed with Parkinson's disease or those who are not candidates for deep brain stimulation may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate predictions of who will benefit from deep brain stimulation, improving treatment outcomes for Parkinson's disease patients.
How similar studies have performed: Previous studies have shown promise in using advanced imaging techniques to predict treatment outcomes in various neurological conditions, suggesting that this approach may yield valuable insights for Parkinson's disease as well.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Morrison, Melanie a — University of California, San Francisco
- Study coordinator: Morrison, Melanie a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.