Using advanced MRI to predict how aggressive kidney tumors are
Translating Hyperpolarized 13C Metabolic MRI to Predict Renal Tumor Aggressiveness
This study is testing a new type of MRI that uses a special substance to help doctors see how active kidney tumors are, which could help them tell apart harmless tumors from more serious ones, ultimately making it easier for patients to avoid unnecessary surgeries.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11002704 on NIH RePORTER |
What this research studies
This research focuses on using hyperpolarized 13C pyruvate MRI as a noninvasive imaging technique to assess the aggressiveness of kidney tumors. By analyzing the metabolic activity of these tumors, the study aims to differentiate between benign and malignant tumors more accurately than current methods. This could help reduce unnecessary surgeries and associated risks for patients with indolent tumors. The approach seeks to improve patient management by providing clearer insights into tumor behavior.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with localized renal tumors who are facing uncertainty regarding the aggressiveness of their condition.
Not a fit: Patients with advanced renal cancer or those who do not have renal tumors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and better treatment decisions for patients with kidney tumors.
How similar studies have performed: Other research has shown promise in using advanced imaging techniques for cancer diagnosis, suggesting that this approach may also yield successful outcomes.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Wang, Zhen Jane — University of California, San Francisco
- Study coordinator: Wang, Zhen Jane
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.