Using advanced MRI to improve treatment for acute ischemic stroke patients
Ultrafast Quantitative pH MRI for Acute Ischemic Stroke Patients
This study is looking at a new way to use special MRI scans to find brain areas that are still healthy enough to treat after a stroke, even if it's been a while since the stroke happened, so that more patients can get the help they need to recover.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10794203 on NIH RePORTER |
What this research studies
This research focuses on enhancing the treatment of acute ischemic stroke by utilizing ultrafast quantitative pH MRI to identify brain tissue that is at risk but still viable for treatment. The approach aims to improve the accuracy of identifying salvageable brain tissue, which is crucial for effective reperfusion therapy. By optimizing imaging protocols, the study seeks to provide better guidance for treatment decisions, especially for patients who present beyond the standard treatment time windows. This could potentially expand the eligibility for life-saving therapies in stroke patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients experiencing acute ischemic stroke, particularly those who present beyond the typical treatment time frames.
Not a fit: Patients who have experienced hemorrhagic strokes or those with conditions that contraindicate MRI may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly increase the number of stroke patients who can receive effective treatment, potentially reducing morbidity and mortality associated with strokes.
How similar studies have performed: Previous studies have shown promise in using advanced MRI techniques for stroke assessment, but this specific approach is novel and aims to refine existing methods.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Heo, Hye Young — Johns Hopkins University
- Study coordinator: Heo, Hye Young
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.