Using advanced MRI to detect brain changes in Alzheimer's disease
7T MRI as a potential tool for detection of pathology in Alzheimer's disease
This study is looking at a special type of MRI scan to help find harmful plaques in the brains of people with Alzheimer's disease, which could lead to earlier and more accurate diagnoses.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10907725 on NIH RePORTER |
What this research studies
This research investigates the use of 7 Tesla MRI technology to identify amyloid-beta plaques in the brains of Alzheimer's disease patients. By focusing on the accumulation of iron near these plaques, the study aims to enhance the imaging techniques available for detecting these pathological markers. Patients will undergo non-invasive MRI scans that can provide detailed insights into the presence of these plaques, potentially leading to earlier and more accurate diagnoses. The research seeks to develop specialized imaging sequences that improve the visualization of these biomarkers.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or those showing early signs of cognitive decline.
Not a fit: Patients with other forms of dementia or those who do not have any cognitive impairment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic methods for Alzheimer's disease, allowing for earlier intervention and better management of the condition.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for detecting Alzheimer's-related changes, but the application of 7T MRI for this purpose is relatively novel.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Alipour, Akbar — Icahn School of Medicine at Mount Sinai
- Study coordinator: Alipour, Akbar
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.