Using advanced MRI techniques to study sodium levels in mild brain injuries
Optimized Sodium MR Imaging at Clinical Field Strength to Study in vivo Sodium Signal in Mild Traumatic Brain Injury
This study is looking at how new MRI techniques can help us understand brain changes in people with Mild Traumatic Brain Injury (MTBI) by measuring sodium levels, which could lead to better treatments for this common condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11058399 on NIH RePORTER |
What this research studies
This research focuses on utilizing advanced sodium MRI (NaMRI) and proton diffusion MRI to identify imaging biomarkers in patients with Mild Traumatic Brain Injury (MTBI). By measuring sodium levels in the brain, the study aims to uncover the underlying mechanisms of MTBI, which has been a significant public health issue. The research leverages recent technological advancements to improve the signal quality of NaMRI, making it feasible to study clinical populations. The findings could lead to new treatment pathways for MTBI, addressing the current gaps in understanding and managing this condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Mild Traumatic Brain Injury.
Not a fit: Patients with severe traumatic brain injuries or other neurological conditions unrelated to MTBI may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide critical insights into the mechanisms of mild traumatic brain injury and pave the way for new treatment options.
How similar studies have performed: Previous studies have shown promising results in using sodium channel blockade in animal models of MTBI, indicating potential for success in this novel approach.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Lui, Yvonne W — New York University School of Medicine
- Study coordinator: Lui, Yvonne W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.