Using advanced MRI techniques to improve treatment for head and neck cancer
Leveraging Hyperpolarized MRI for Precision Oncology Approaches in Head and Neck Cancer
This study is looking at how a special type of imaging can help doctors see how well chemotherapy is working for patients with head and neck cancer, so they can tailor treatments to those who will benefit the most.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10918285 on NIH RePORTER |
What this research studies
This research focuses on head and neck squamous cell carcinoma (HNSCC), a major cause of cancer deaths. It aims to improve treatment outcomes by using hyperpolarized magnetic resonance imaging (HP-MRI) to monitor how tumors respond to chemotherapy, specifically cisplatin. By observing changes in tumor metabolism during treatment, the researchers hope to identify which patients are likely to benefit from therapy and to optimize treatment plans accordingly. This approach is designed to be minimally invasive, providing real-time insights into tumor behavior.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with head and neck squamous cell carcinoma who are undergoing treatment with cisplatin.
Not a fit: Patients with head and neck cancer who are not receiving cisplatin or those with non-squamous cell carcinoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment strategies for patients with head and neck cancer.
How similar studies have performed: Previous research has shown promising results using similar imaging techniques to assess tumor response, indicating potential for success in this novel application.
Where this research is happening
Houston, United States
- University of Tx Md Anderson Can Ctr — Houston, United States (Active)
Researchers
- Principal investigator: Lai, Stephen Y — University of Tx Md Anderson Can Ctr
- Study coordinator: Lai, Stephen Y
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.