Using advanced MRI techniques to improve epilepsy diagnosis
MR Fingerprinting for Epilepsy
['FUNDING_R01'] · CLEVELAND CLINIC LERNER COM-CWRU · NIH-11072313
This study is looking at a new way to find tiny brain changes in people with focal epilepsy who have normal MRI scans, using a special technique called MR Fingerprinting, to help doctors better understand their condition and improve treatment options.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CLEVELAND CLINIC LERNER COM-CWRU (nih funded) |
| Locations | 1 site (CLEVELAND, UNITED STATES) |
| Trial ID | NIH-11072313 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing the detection of subtle brain lesions in patients with focal epilepsy who do not show identifiable lesions on standard MRI scans. By employing a novel technique called MR Fingerprinting, the study aims to create detailed tissue property maps that can reveal changes in brain structure associated with epilepsy. The approach involves developing a fast and efficient imaging pipeline that allows for quick analysis and interpretation of MRI data, potentially leading to better treatment outcomes for patients. The goal is to make this advanced imaging technique widely available in clinical settings.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults and children over 21 years old who have pharmacoresistant focal epilepsy and have undergone presurgical evaluation.
Not a fit: Patients with epilepsy who have identifiable lesions on conventional MRI scans may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the diagnosis and treatment outcomes for patients with epilepsy who currently have no identifiable lesions on traditional MRI scans.
How similar studies have performed: Previous research has shown promise in using advanced MRI techniques for detecting subtle brain abnormalities, indicating that this approach could lead to significant advancements in epilepsy diagnosis.
Where this research is happening
CLEVELAND, UNITED STATES
- CLEVELAND CLINIC LERNER COM-CWRU — CLEVELAND, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WANG, ZHONG IRENE — CLEVELAND CLINIC LERNER COM-CWRU
- Study coordinator: WANG, ZHONG IRENE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.