Using advanced MRI techniques to detect early signs of Alzheimer's disease
Quantitative Magnetization Transfer Imaging for Early Detection of Alzheimer's Disease
This study is testing a new MRI method that could help spot early signs of Alzheimer's disease by looking for tiny changes in brain tissue, making it easier and quicker to diagnose the condition without needing more invasive tests.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10868594 on NIH RePORTER |
What this research studies
This research focuses on developing a new MRI-based technique called quantitative magnetization transfer imaging to identify early changes in brain tissue associated with Alzheimer's disease. By detecting microstructural changes, such as the presence of amyloid beta protein, this method aims to provide a non-invasive and rapid diagnostic tool that could improve early detection of Alzheimer's. The study will optimize imaging techniques to enhance sensitivity and accuracy, potentially offering a more reliable alternative to current diagnostic methods like amyloid PET scans.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who are at risk for Alzheimer's disease or those showing early signs of cognitive decline.
Not a fit: Patients with advanced Alzheimer's disease or those without any cognitive impairment are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate diagnosis of Alzheimer's disease, allowing for timely intervention and management.
How similar studies have performed: Previous research has shown promising results using similar imaging techniques for detecting Alzheimer's pathology, indicating potential for success in this approach.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Mao, Andrew — New York University School of Medicine
- Study coordinator: Mao, Andrew
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.