NIH-funded research Sbir 1 grant

Using advanced MRI techniques to better understand and monitor Multiple Sclerosis

Official title: Reporting Quantitative Microstructural MRI Metrics to Stage and Monitor Multiple Sclerosis

Funded at Microstructure Imaging, INC. · NIH-10920523 · Data updated 2026-11-12

This study is looking to make it easier to track changes in the brains of people with Multiple Sclerosis by using advanced MRI techniques, which could help doctors better understand how the disease is affecting you and improve your care.

Quick facts

Grant typeSbir 1 grant
Study typeNIH-funded research
Funding institutionMicrostructure Imaging, INC.
NIH-funded
Lab location1 site (New York, United States)
Project startSeptember 10, 2024
Project endAugust 31, 2026
Funding year2024
Award (this year)$353,942
NIH project number1R43NS137871-01
Project IDNIH-10920523 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals aged 21 and older who have been diagnosed with Multiple Sclerosis.

Less likely to help

Patients with other neurological conditions or those under 21 years old may not benefit from this research.

What this research studies

This research focuses on improving the way Multiple Sclerosis (MS) is monitored using advanced MRI techniques. It aims to develop new quantitative MRI biomarkers that can provide more precise information about the microscopic changes in the brain associated with MS. By analyzing diffusion MRI data, the researchers hope to differentiate between inflammatory and degenerative processes in the brain, which could lead to more accurate assessments of disease progression. The study will also create a database of normative MRI parameters to help interpret individual patient results.

Why it matters

Potential benefit: If successful, this research could lead to more accurate monitoring of Multiple Sclerosis, allowing for better treatment decisions and improved patient outcomes.

How similar studies have gone: Previous research has shown promise in using advanced MRI techniques for monitoring neurological diseases, suggesting that this approach could be effective.

Where this research is happening

  • Microstructure Imaging, INC.
    New York, United States
    Active

Researchers

  • Principal investigator: Lemberskiy, Grigoriy — Microstructure Imaging, INC.
  • Study coordinator: Lemberskiy, Grigoriy

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.