Using advanced MRI techniques to assess heart function and pressures in patients with heart failure.
MRI Metrics of Diastolic Dysfunction at Rest and Stress Validated by Estimated Pressures
This study is working on new MRI techniques to help doctors better understand and diagnose heart failure with preserved ejection fraction (HFpEF), a condition that makes it hard for the heart to fill with blood, so that patients can receive better care and treatment.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-11174986 on NIH RePORTER |
What this research studies
This research focuses on improving the diagnosis of heart failure with preserved ejection fraction (HFpEF), a condition where the heart struggles to fill with blood, leading to symptoms like breathlessness. The study aims to develop advanced MRI methods that can accurately measure diastolic function and estimate cardiac pressures, which are crucial for understanding and treating HFpEF. By utilizing deep learning techniques and innovative MRI imaging, the researchers hope to enhance the accuracy of heart function assessments, ultimately aiding in better patient management and therapy development.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with heart failure with preserved ejection fraction (HFpEF) who experience unexplained breathlessness.
Not a fit: Patients with heart failure with reduced ejection fraction or those without heart failure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and better treatment options for patients suffering from heart failure.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for cardiac assessments, suggesting potential success for this novel approach.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Peters, Dana C — Yale University
- Study coordinator: Peters, Dana C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.