Using advanced models to analyze genomic data for personalized cancer treatment
Bayesian Network-Based Integrative Genomics Methods for Precision Medicine
This study is exploring new ways to combine and understand genetic information to help create better, personalized treatments for colorectal cancer, so patients can get more effective care based on the specific details of their disease.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10793662 on NIH RePORTER |
What this research studies
This research focuses on developing innovative methods to integrate and analyze complex genomic data from multiple sources to improve precision medicine, particularly for colorectal cancer. By identifying key biological pathways and their regulators, the research aims to uncover new therapeutic strategies tailored to specific cancer subtypes. Patients will benefit from a deeper understanding of their disease at the molecular level, which could lead to more effective treatment options. The approach involves sophisticated statistical models that connect genetic and epigenetic factors to disease pathways.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with colorectal cancer, particularly those with specific molecular subtypes.
Not a fit: Patients with cancers other than colorectal cancer or those without identifiable molecular subtypes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment strategies for patients with colorectal cancer.
How similar studies have performed: Previous research has shown promise in using integrative genomic approaches to improve cancer treatment, indicating that this methodology has potential for success.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Morris, Jeffrey S — University of Pennsylvania
- Study coordinator: Morris, Jeffrey S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.