Using advanced microscopy to improve skin cancer diagnosis and treatment
Two photon fluorescence microscopy for dermatologic surgery and biopsy
This study is testing a new way to quickly and accurately diagnose and treat nonmelanoma skin cancer using a special imaging technique, which could help patients get the care they need faster and with fewer trips to the doctor, especially for those living in rural areas.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-11053496 on NIH RePORTER |
What this research studies
This research focuses on enhancing the diagnosis and treatment of nonmelanoma skin cancer through the use of two photon fluorescence microscopy (TPFM). By combining TPFM with rapid molecular labeling, the research aims to evaluate skin tissue histology much faster than traditional methods, potentially reducing the need for multiple clinic visits and surgeries. The approach seeks to address the inefficiencies in current diagnostic processes that can delay treatment and lead to suboptimal care, especially for patients in rural areas. Preliminary studies suggest that TPFM can provide accurate evaluations comparable to conventional histology.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients undergoing biopsy or treatment for nonmelanoma skin cancer.
Not a fit: Patients with melanoma or other types of skin cancer not covered by this research may not receive any benefit.
Why it matters
Potential benefit: If successful, this research could lead to quicker and more accurate diagnoses for skin cancer, improving patient outcomes and access to timely treatment.
How similar studies have performed: Other research has shown promising results with advanced imaging techniques in similar contexts, indicating potential for success in this novel approach.
Where this research is happening
Rochester, United States
- University of Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Giacomelli, Michael Gene — University of Rochester
- Study coordinator: Giacomelli, Michael Gene
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.