Using advanced methods to analyze large genetic datasets for public health.
Phylogenetic and computational methods for accurate and efficient analyses of large-scale metagenomics datasets
This study is all about making it easier to understand the genetic information from different organisms, which can help us find germs, learn more about the bacteria in our bodies, and keep track of different species, especially in relation to the SARS-CoV-2 virus, using a new user-friendly software called tronko.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Hawaii at Manoa NIH-funded |
| Lab location | 1 site (Honolulu, United States) |
| Project ID | NIH-11259170 on NIH RePORTER |
What this research studies
This research focuses on improving the analysis of metagenomics data, which involves studying the combined genetic material of organisms in a community. By utilizing advanced statistical and computational techniques, the project aims to enhance the detection of pathogens, analyze the human microbiome, and monitor biodiversity. A key component of the research is the development of an open-source software called tronko, which allows for efficient taxonomic classification using large-scale genetic databases. This work is particularly relevant for understanding and monitoring the SARS-CoV-2 virus.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals interested in the genetic analysis of pathogens or those affected by infectious diseases.
Not a fit: Patients with conditions unrelated to infectious diseases or those not involved in genetic research may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better detection and monitoring of infectious diseases, including COVID-19, ultimately improving public health responses.
How similar studies have performed: Other research has successfully utilized similar computational approaches in metagenomics, indicating a promising potential for this project.
Where this research is happening
Honolulu, United States
- University of Hawaii at Manoa — Honolulu, United States (Active)
Researchers
- Principal investigator: Pipes, Lenore — University of Hawaii at Manoa
- Study coordinator: Pipes, Lenore
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.