Using advanced imaging to understand lung fibrosis
PET-MR Imaging of pulmonary fibrosis
This study is looking at how special imaging techniques can help spot early signs of lung scarring in people with pulmonary fibrosis and see how well treatments are working, so patients can get better care for their condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10890042 on NIH RePORTER |
What this research studies
This research focuses on using a combination of PET and MR imaging techniques to identify and quantify molecular changes in the lungs associated with pulmonary fibrosis. By employing a specialized PET probe that targets type I collagen, the study aims to detect early signs of fibrosis and assess how well patients respond to anti-fibrotic treatments. This approach seeks to improve the accuracy of diagnosing and monitoring the progression of idiopathic pulmonary fibrosis (IPF), a serious lung disease with limited treatment options. Patients may undergo imaging procedures to help researchers gather data on their condition and treatment responses.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with idiopathic pulmonary fibrosis or those exhibiting symptoms of lung fibrosis.
Not a fit: Patients with other types of lung diseases or those who do not have pulmonary fibrosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier diagnosis and more effective monitoring of treatment for patients with pulmonary fibrosis.
How similar studies have performed: Previous studies have shown promise in using molecular imaging techniques for detecting fibrosis, indicating that this approach may be effective.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Caravan, Peter D — Massachusetts General Hospital
- Study coordinator: Caravan, Peter D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.