Using advanced imaging to understand and treat pulmonary fibrosis
Multimodal quantitative PET/MR imaging of pulmonary fibrosis
This study is looking at a serious lung disease called idiopathic pulmonary fibrosis (IPF) to find out how it progresses and how well new treatments work, using special imaging techniques in mice to help identify better ways to treat patients like you.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10904731 on NIH RePORTER |
What this research studies
This research investigates idiopathic pulmonary fibrosis (IPF), a severe lung disease, by employing multimodal quantitative PET/MR imaging techniques. The goal is to better understand the disease's progression and response to treatments by identifying specific molecular targets in the lungs. By using advanced imaging, researchers aim to improve patient stratification and monitor how well new therapies are working, potentially leading to more effective treatments. The study will utilize mouse models to explore the effects of targeting specific pathways involved in lung fibrosis.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with idiopathic pulmonary fibrosis who may benefit from new therapeutic approaches.
Not a fit: Patients with other forms of lung disease or those not diagnosed with pulmonary fibrosis may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment options for patients with pulmonary fibrosis.
How similar studies have performed: Previous research using multimodal imaging techniques has shown promise in other diseases, suggesting potential for success in this novel application for pulmonary fibrosis.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Akam-Baxter, Eman — Massachusetts General Hospital
- Study coordinator: Akam-Baxter, Eman
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.