Using advanced imaging to understand and treat IDH-mutant gliomas
Official title: Molecular MR-PET to characterize malignant transformation and identify therapeutic vulnerabilities in human IDH-mutant gliomas
Funded at University of California Los Angeles · NIH-10930013 · Data updated 2026-11-12
This study is looking for early signs that a type of brain tumor called IDH-mutant gliomas might be getting worse, using special MRI scans to spot changes that could help doctors make better treatment decisions for patients.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $41,359 |
| NIH project number | 5F30CA284809-02 |
| Project ID | NIH-10930013 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with IDH-mutant gliomas, particularly those in the early stages of the disease.
✕Less likely to help
Patients with IDH-wild-type gliomas or those at advanced stages of glioma may not benefit from this research.
What this research studies
This research focuses on identifying early signs of malignant transformation in IDH-mutant gliomas, a type of brain tumor. By utilizing advanced magnetic resonance imaging (MRI) techniques, the study aims to detect changes in tumor characteristics that indicate a shift from low-grade to high-grade gliomas. This non-invasive approach could help in timely intervention and treatment adjustments for patients. The research seeks to improve the understanding of the tumor microenvironment and its implications for patient care.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection of tumor progression in patients with IDH-mutant gliomas, allowing for more effective treatment strategies.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques for tumor characterization, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Cho, Nicholas S. — University of California Los Angeles
- Study coordinator: Cho, Nicholas S.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.