Using advanced imaging to track brain changes after spinal cord injury
SV2A PET in Spinal Cord Injury Imaging
This study is looking at a new way to take pictures of the brain and spinal cord to see how they change after a spinal cord injury, helping us understand recovery better and test new treatments for people who have experienced these injuries.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10873830 on NIH RePORTER |
What this research studies
This research investigates the use of a new imaging technique called SV2A PET to monitor changes in the brain and spinal cord following traumatic spinal cord injuries. By applying this advanced imaging method, researchers aim to gather detailed information about synaptic density and neuroplasticity, which are crucial for understanding recovery processes. The study will involve both animal models and human participants to validate the effectiveness of SV2A PET in assessing the progression of spinal cord injuries and the impact of potential treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have experienced a traumatic spinal cord injury and are seeking innovative treatment options.
Not a fit: Patients with non-traumatic spinal cord conditions or those who do not have access to the research site may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic and prognostic tools for spinal cord injury, enhancing treatment strategies and recovery outcomes for patients.
How similar studies have performed: Previous studies using SV2A PET imaging have shown promise in other neuropsychiatric disorders, suggesting potential for success in this novel application for spinal cord injury.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Cai, Zhengxin — Yale University
- Study coordinator: Cai, Zhengxin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.