Using advanced imaging to improve skin cancer treatment accuracy
Cherenkov imaging incorporating 3D surface imaging for TSET
This study is looking to improve skin treatment for patients with mycosis fungoides by using a special imaging technology to help make sure they get the right amount of radiation during therapy, even if they move around a bit.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10904881 on NIH RePORTER |
What this research studies
This research focuses on enhancing total skin electron therapy (TSET) for patients with mycosis fungoides by incorporating Cherenkov imaging technology. It aims to address challenges related to patient positioning and movement during treatment, which can lead to inaccurate radiation doses. By capturing Cherenkov emissions from the skin, the study seeks to provide real-time monitoring of radiation delivery, ensuring that patients receive the correct dose. The project will involve clinical trials to validate this imaging technique and develop necessary corrections for accurate dose documentation.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with mycosis fungoides who are undergoing total skin electron therapy.
Not a fit: Patients with skin conditions other than mycosis fungoides or those not receiving total skin electron therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the accuracy of radiation therapy for skin cancer patients, leading to better treatment outcomes.
How similar studies have performed: Previous research has shown promise in using imaging technologies for radiation therapy, suggesting that this approach could lead to meaningful advancements in treatment accuracy.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Zhu, Timothy C. — University of Pennsylvania
- Study coordinator: Zhu, Timothy C.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.