Using advanced imaging to improve radiation therapy for head and neck cancer

Development of functional magnetic resonance imaging-guided adaptive radiotherapy for head and neck cancer patients using novel MR-Linac device

NIH-funded research University of Tx Md Anderson Can Ctr · NIH-10623179

This study is testing a new device that helps doctors give better radiation treatment for head and neck cancer by using daily scans to see how the tumor is changing, so they can adjust the treatment right away for the best results and fewer side effects.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Tx Md Anderson Can Ctr NIH-funded
Lab location1 site (Houston, United States)
Project IDNIH-10623179 on NIH RePORTER

What this research studies

This research focuses on enhancing radiation therapy for head and neck cancer patients by utilizing a novel device that combines MRI and a linear accelerator. The approach involves daily imaging to identify how tumors respond to treatment, allowing for real-time adjustments to radiation plans. By adapting therapy based on the tumor's biological changes, the goal is to maximize treatment effectiveness while minimizing side effects. Patients will benefit from a more personalized treatment strategy that could lead to better outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with head and neck cancers who are undergoing radiation therapy.

Not a fit: Patients with non-cancerous conditions or those not receiving radiation therapy for head and neck cancers may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective radiation treatments with fewer side effects for head and neck cancer patients.

How similar studies have performed: Previous studies have shown promise in using functional imaging techniques to adapt radiation therapy, indicating that this approach could be effective.

Where this research is happening

Houston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancersneoplasm/cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.