Using advanced imaging to improve radiation therapy for glioblastoma in small animals

Quantitative bioluminescence tomography for pre-clinical radiotherapy

NIH-funded research Ut Southwestern Medical Center · NIH-10630901

This study is looking at new ways to make radiation therapy for glioblastoma better by using advanced imaging techniques to help doctors target tumors more accurately, which could lead to improved treatment results.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUt Southwestern Medical Center NIH-funded
Lab location1 site (Dallas, United States)
Project IDNIH-10630901 on NIH RePORTER

What this research studies

This research focuses on enhancing radiation therapy for glioblastoma by integrating advanced imaging techniques. It utilizes a small-animal radiation research platform that combines cone-beam CT with 3D bioluminescence tomography to improve the targeting of tumors. By providing better localization of soft tissue tumors, this approach aims to refine pre-clinical studies and improve treatment outcomes. The research seeks to address the limitations of current imaging methods to ensure more precise irradiation of tumors in animal models.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with glioblastoma or those involved in pre-clinical studies related to this condition.

Not a fit: Patients with conditions other than glioblastoma or those not involved in pre-clinical research may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective radiation therapy techniques for glioblastoma, potentially improving patient outcomes.

How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for tumor targeting, indicating potential success for this novel approach.

Where this research is happening

Dallas, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.