Using advanced imaging to identify effective cancer treatments
Multiplexed time domain fluorescence tomography of tumor biomarkers during immunotherapy
This study is looking at how new imaging technology can help doctors keep an eye on tumor changes in patients with triple negative breast cancer who are receiving immunotherapy, making it easier to see who might benefit from the treatment and reducing the chances of side effects from therapies that don’t work.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts Eye and Ear Infirmary NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10810859 on NIH RePORTER |
What this research studies
This research investigates how advanced imaging techniques can be used to monitor tumor biomarkers in patients undergoing immunotherapy for cancers like triple negative breast cancer. By utilizing multiplexed time domain fluorescence tomography, the study aims to provide a non-invasive way to track changes in tumor characteristics over time, which can help identify which patients are likely to respond to treatment. This approach seeks to improve patient outcomes by minimizing unnecessary side effects from ineffective therapies and enhancing the evaluation of new treatment combinations.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with triple negative breast cancer who are considering immunotherapy options.
Not a fit: Patients with cancers other than triple negative breast cancer or those not eligible for immunotherapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized cancer treatments, allowing patients to receive therapies that are more likely to be effective for them.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for monitoring treatment responses, indicating that this approach could be effective.
Where this research is happening
Boston, United States
- Massachusetts Eye and Ear Infirmary — Boston, United States (Active)
Researchers
- Principal investigator: Kumar, Anand T.n. — Massachusetts Eye and Ear Infirmary
- Study coordinator: Kumar, Anand T.n.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.