Using advanced imaging to find biomarkers for eye diseases
Official title: OCT-based functional biomarkers for degenerative diseases of the photoreceptor-RPE-choroid neurovascular unit
Funded at University of California at Davis · NIH-10915567 · Data updated 2026-11-12
This study is looking at new ways to take pictures of the eye to help doctors better understand and track eye diseases like age-related macular degeneration and inherited retinal conditions, so if you join, you’ll help improve how we diagnose and treat these issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | September 30, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $543,570 |
| NIH project number | 5R01EY034340-02 |
| Project ID | NIH-10915567 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation include individuals diagnosed with age-related macular degeneration or inherited retinal degenerations.
✕Less likely to help
Patients with other unrelated eye conditions or those without any retinal diseases may not benefit from this research.
What this research studies
This research focuses on developing new imaging techniques to identify functional biomarkers for degenerative eye diseases, particularly age-related macular degeneration (AMD) and inherited retinal degenerations (IRDs). By utilizing a next-generation optoretinography system, the study aims to provide noninvasive and objective measurements of retinal function, which could help in understanding disease progression and recovery. Patients may undergo advanced imaging procedures to assess their retinal health and contribute to the development of new diagnostic tools. The goal is to improve the understanding of these conditions and ultimately lead to better treatment options.
Why it matters
Potential benefit: If successful, this research could lead to the development of new diagnostic tools that improve the management and treatment of degenerative eye diseases.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques for retinal diseases, indicating that this approach could yield valuable insights.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Jonnal, Ravi S. — University of California at Davis
- Study coordinator: Jonnal, Ravi S.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.