Using advanced imaging to find biomarkers for eye diseases

OCT-based functional biomarkers for degenerative diseases of the photoreceptor-RPE-choroid neurovascular unit

NIH-funded research University of California at Davis · NIH-10915567

This study is looking at new ways to take pictures of the eye to help doctors better understand and track eye diseases like age-related macular degeneration and inherited retinal conditions, so if you join, you’ll help improve how we diagnose and treat these issues.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California at Davis NIH-funded
Lab location1 site (Davis, United States)
Project IDNIH-10915567 on NIH RePORTER

What this research studies

This research focuses on developing new imaging techniques to identify functional biomarkers for degenerative eye diseases, particularly age-related macular degeneration (AMD) and inherited retinal degenerations (IRDs). By utilizing a next-generation optoretinography system, the study aims to provide noninvasive and objective measurements of retinal function, which could help in understanding disease progression and recovery. Patients may undergo advanced imaging procedures to assess their retinal health and contribute to the development of new diagnostic tools. The goal is to improve the understanding of these conditions and ultimately lead to better treatment options.

Who could benefit from this research

Good fit: Ideal candidates for participation include individuals diagnosed with age-related macular degeneration or inherited retinal degenerations.

Not a fit: Patients with other unrelated eye conditions or those without any retinal diseases may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to the development of new diagnostic tools that improve the management and treatment of degenerative eye diseases.

How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for retinal diseases, indicating that this approach could yield valuable insights.

Where this research is happening

Davis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.