Using advanced imaging to diagnose and manage irregular corneas

Artificial Intelligence Assisted Optical Coherence Tomography for Differential Diagnosis and Management of Irregular Corneas

NIH-funded research Oregon Health & Science University · NIH-11050128

This study is all about helping people with eye conditions that can affect their vision by using a special 3D imaging tool to better understand and treat different corneal problems, so patients can get the right care for their specific needs.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOregon Health & Science University NIH-funded
Lab location1 site (Portland, United States)
Project IDNIH-11050128 on NIH RePORTER

What this research studies

This research focuses on improving the diagnosis and treatment of various corneal conditions that can affect vision. By utilizing advanced optical coherence tomography (OCT), a 3D imaging technology, the project aims to accurately differentiate between different types of corneal irregularities, such as keratoconus and endothelial dysfunction. The study will develop new metrics for staging and monitoring these conditions, which can often appear similar but require different treatment approaches. Patients will benefit from enhanced early detection and tailored management strategies based on their specific corneal issues.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals experiencing vision problems related to corneal irregularities, such as keratoconus or corneal edema.

Not a fit: Patients with healthy corneas or those whose vision issues are unrelated to corneal shape or thickness may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate diagnoses and better treatment options for patients with irregular corneas.

How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for diagnosing corneal conditions, suggesting that this approach could yield significant advancements.

Where this research is happening

Portland, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.