Using advanced imaging to diagnose and assess treatment for lung fibrosis
In vivo endobronchial OCT for IPF diagnosis and therapy response assessment
This study is looking at a new imaging technique to help doctors spot idiopathic pulmonary fibrosis (IPF) earlier and see how well treatments are working, so patients can get the right care sooner.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10847332 on NIH RePORTER |
What this research studies
This research focuses on improving the diagnosis and treatment assessment of idiopathic pulmonary fibrosis (IPF), a serious lung disease. It aims to utilize endobronchial optical coherence tomography (EB-OCT), a cutting-edge imaging technique, to provide detailed, microscopic images of lung tissue. By doing so, the research seeks to identify IPF at earlier stages than current methods allow, which can lead to timely and appropriate treatment decisions. This approach could also help monitor how well patients are responding to their therapies over time.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suspected of having idiopathic pulmonary fibrosis or those already diagnosed with the condition who require assessment of their treatment response.
Not a fit: Patients with other forms of lung disease that do not involve idiopathic pulmonary fibrosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate diagnoses of IPF, ultimately improving patient outcomes and treatment effectiveness.
How similar studies have performed: Other research has shown promise in using advanced imaging techniques for lung diseases, but the specific application of EB-OCT for IPF diagnosis and monitoring is relatively novel.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Hariri, Lida P — Massachusetts General Hospital
- Study coordinator: Hariri, Lida P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.