Using advanced imaging to detect oral cancer early
Endogenous fluorescence lifetime endoscopy for early detection of oral cancer and dysplasia
This study is testing a new imaging method to help doctors spot oral cancer and related conditions earlier by looking for specific signs in the mouth, which could lead to better and less invasive treatment options for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Oklahoma NIH-funded |
| Lab location | 1 site (Norman, United States) |
| Project ID | NIH-10686883 on NIH RePORTER |
What this research studies
This research focuses on developing a new imaging technique called endogenous fluorescence lifetime imaging (FLIM) to improve the early detection of oral cancer and dysplasia. By analyzing specific biomarkers in the oral cavity, the study aims to enhance the sensitivity and specificity of cancer diagnosis, which is crucial for timely treatment. The approach seeks to differentiate between benign lesions and early-stage cancers, potentially allowing for less invasive treatment options. Patients will be monitored using this innovative imaging tool to identify cancerous changes at an earlier stage than current methods allow.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for oral cancer, particularly those with lesions in the oral cavity that may be dysplastic or cancerous.
Not a fit: Patients with advanced oral cancer or those who do not have any lesions in the oral cavity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate diagnoses of oral cancer, significantly improving survival rates and treatment outcomes.
How similar studies have performed: While there have been various screening tools for oral cancer, this specific approach using FLIM is novel and has not been widely tested in clinical settings.
Where this research is happening
Norman, United States
- University of Oklahoma — Norman, United States (Active)
Researchers
- Principal investigator: Jo, Javier Antonio — University of Oklahoma
- Study coordinator: Jo, Javier Antonio
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.