Using advanced imaging to detect kidney transplant injury in children
IMPAKT Study: Imaging Modalities in Pediatric Assessments of Kidney Transplants
This study is looking at new ways to use MRI and ultrasound to spot problems in kidney transplants for kids, helping doctors find issues early without needing painful procedures, so they can better care for children with kidney disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11058468 on NIH RePORTER |
What this research studies
This research investigates the use of innovative MRI and ultrasound imaging techniques to identify kidney transplant injuries in children. By focusing on non-invasive methods, the study aims to find reliable biomarkers that can indicate the risk of kidney transplant failure. This is particularly important for children with end-stage kidney disease, who often face higher risks with invasive procedures like biopsies. The goal is to improve the management of kidney transplants and enhance patient outcomes through early detection of potential issues.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who have received a kidney transplant and are at risk for allograft injury.
Not a fit: Patients who have not undergone kidney transplantation or are older than 21 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better monitoring of kidney transplants in children, reducing the need for invasive biopsies and improving long-term transplant survival.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for similar applications, indicating potential for success in this novel approach.
Where this research is happening
Philadelphia, United States
- Children's Hosp of Philadelphia — Philadelphia, United States (Active)
Researchers
- Principal investigator: Viteri Baquerizo, Bernarda — Children's Hosp of Philadelphia
- Study coordinator: Viteri Baquerizo, Bernarda
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.