Using advanced imaging to assess the mechanics of spinal discs
Magnetic Resonance Elastography as a Personalized Assessment of Intervertebral Disc Mechanics
This study is looking at a special imaging technique called magnetic resonance elastography (MRE) to help understand how the discs in your back might be causing your low back pain, by checking for any changes or problems in those discs without any surgery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project ID | NIH-10823365 on NIH RePORTER |
What this research studies
This research investigates the use of magnetic resonance elastography (MRE) to evaluate the mechanical properties of intervertebral discs in patients with low back pain. By measuring how strain waves propagate through the discs, the study aims to identify internal disruptions and changes in tissue stiffness that may contribute to pain. The approach is non-invasive and seeks to improve the accuracy of diagnosing and treating chronic low back pain by providing a more detailed understanding of disc degeneration. The research will also focus on optimizing imaging techniques to enhance clinical application.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing chronic low back pain, particularly those with suspected intervertebral disc degeneration.
Not a fit: Patients with acute low back pain or those without any disc-related issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and personalized treatment plans for patients suffering from low back pain.
How similar studies have performed: Previous studies have shown that magnetic resonance elastography can effectively identify tissue properties in various conditions, suggesting a promising avenue for this application in low back pain.
Where this research is happening
Columbus, UNITED STATES
- Ohio State University — Columbus, United States (Active)
Researchers
- Principal investigator: Walter, Benjamin a. — Ohio State University
- Study coordinator: Walter, Benjamin a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.