Using advanced imaging technology to improve cancer risk assessment for lung nodules

Assessment of a Radiomics-Based Computer-Aided Diagnosis Tool for Cancer Risk Stratification of Pulmonary Nodules

NIH-funded research University of Pennsylvania · NIH-10890087

This study is testing a new computer tool that helps doctors better understand lung nodules seen in CT scans, making it easier to spot lung cancer early and avoid unnecessary procedures, so patients can get the right care they need.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-10890087 on NIH RePORTER

What this research studies

This research focuses on enhancing the diagnostic evaluation of pulmonary nodules (PNs) to improve early detection of lung cancer while reducing unnecessary procedures. It utilizes a radiomics-based computer-aided diagnosis (CAD) tool that analyzes CT imaging data to provide insights that are not visible to the naked eye. By improving the accuracy of malignancy risk estimation, the project aims to help clinicians make better decisions about whether patients need invasive biopsies or can be monitored with imaging. The research is part of a comprehensive career development plan for a physician-scientist dedicated to thoracic oncology.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with pulmonary nodules detected through CT imaging who are at risk for lung cancer.

Not a fit: Patients without pulmonary nodules or those who have already been diagnosed with lung cancer may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate diagnoses of lung cancer, reducing the need for invasive procedures and improving patient outcomes.

How similar studies have performed: Previous research has shown promise in using radiomics for improving diagnostic accuracy, indicating that this approach has potential for success.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.