Using advanced imaging techniques to improve diagnosis of Lewy-body diseases and Alzheimer's disease
Higher Order Convolutional Neural Network for Classification of Lewy-body Diseases and Alzheimers Disease
This study is looking at new ways to take pictures of the brain to help doctors better tell apart conditions like Lewy body dementia, Parkinson's disease, and Alzheimer's, so that patients can get more accurate diagnoses and better care.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project ID | NIH-11023149 on NIH RePORTER |
What this research studies
This research focuses on enhancing the accuracy of diagnosing neurodegenerative disorders such as Lewy body dementia, Parkinson's disease, and Alzheimer's disease through advanced imaging techniques. It employs Diffusion Tensor Imaging (DTI) and High Angular Resolution Diffusion Imaging (HARDI) to capture detailed brain micro-structural features that can differentiate between these conditions more effectively than traditional MRI methods. By combining these advanced imaging modalities, the research aims to improve diagnostic sensitivity and specificity, ultimately leading to better patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing symptoms of dementia, particularly those suspected of having Lewy body dementia, Alzheimer's disease, or Parkinson's disease.
Not a fit: Patients with neurodegenerative disorders not related to Lewy body dementia or Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses of neurodegenerative diseases, allowing for timely and appropriate treatment for patients.
How similar studies have performed: Previous research has shown promising results using advanced imaging techniques for differentiating between stages of Alzheimer's disease and other neurodegenerative disorders.
Where this research is happening
Gainesville, United States
- University of Florida — Gainesville, United States (Active)
Researchers
- Principal investigator: Vemuri, Baba C — University of Florida
- Study coordinator: Vemuri, Baba C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.