Using advanced imaging techniques to identify early signs of Alzheimer's disease
Machine and deep learning for finding multimodal imaging biomarkers in prodromal AD
This study is looking for people with early signs of Alzheimer's to help us learn more about how their brains work during memory tasks, using advanced imaging techniques that could lead to earlier and more accurate diagnoses of the disease.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland Clinic Lerner Com-Cwru NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-11053501 on NIH RePORTER |
What this research studies
This research aims to develop advanced machine learning algorithms and imaging techniques to better understand brain activity in individuals showing early signs of Alzheimer's disease. By utilizing high-resolution imaging at 7T, the study will investigate how different areas of the brain, particularly the hippocampus, respond during memory tasks. The goal is to create more accurate biomarkers that can help in diagnosing Alzheimer's disease at an earlier stage. Patients will undergo specialized imaging procedures to gather data that can improve our understanding of Alzheimer's pathology.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who are in the prodromal stage of Alzheimer's disease or those at high risk due to age or family history.
Not a fit: Patients with advanced Alzheimer's disease or those without any cognitive impairment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate diagnoses of Alzheimer's disease, allowing for timely interventions.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques and machine learning to identify biomarkers for Alzheimer's disease, indicating that this approach has potential for success.
Where this research is happening
Cleveland, United States
- Cleveland Clinic Lerner Com-Cwru — Cleveland, United States (Active)
Researchers
- Principal investigator: Cordes, Dietmar — Cleveland Clinic Lerner Com-Cwru
- Study coordinator: Cordes, Dietmar
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.