Using advanced imaging during surgery to predict vision recovery after macular hole repair.

Intraoperative imaging of macular hole repair to predict visual function outcomes

NIH-funded research Vanderbilt University · NIH-10653835

This study is looking at how using special imaging during eye surgery for macular holes can help doctors predict how well patients will see afterward, so they can improve the surgery and recovery process.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionVanderbilt University NIH-funded
Lab location1 site (Nashville, UNITED STATES)
Project IDNIH-10653835 on NIH RePORTER

What this research studies

This research investigates how intraoperative imaging can help predict visual outcomes for patients undergoing surgery for macular holes in the eye. By utilizing optical coherence tomography (OCT) during the surgical procedure, the team aims to identify specific changes in the retina that may indicate how well a patient will see after the surgery. The approach focuses on understanding the interactions between surgical instruments and retinal tissue to improve surgical techniques and patient outcomes. Patients will be monitored for their visual recovery post-surgery, providing valuable data on the effectiveness of this imaging method.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who are scheduled for macular hole surgery.

Not a fit: Patients with other unrelated eye conditions or those not undergoing macular hole surgery may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved surgical techniques and better visual outcomes for patients with macular holes.

How similar studies have performed: Previous research has shown that advanced imaging techniques can enhance surgical outcomes in ophthalmology, suggesting a promising avenue for this approach.

Where this research is happening

Nashville, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.