Using advanced imaging and robotic technology to improve heart procedures for stroke prevention

Magnetic Resonance Imaging Guided Robotic Catheter System for Left Atrial Appendage Occlusion Procedures

NIH-funded research Case Western Reserve University · NIH-10895300

This study is looking at a new way to make a heart procedure safer and easier for younger patients with atrial fibrillation, helping to prevent strokes without the need for long-term blood thinners.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCase Western Reserve University NIH-funded
Lab location1 site (Cleveland, United States)
Project IDNIH-10895300 on NIH RePORTER

What this research studies

This research focuses on enhancing the Left Atrial Appendage Occlusion (LAAO) procedure, which is designed to prevent strokes in patients with atrial fibrillation. By utilizing a magnetic resonance imaging guided robotic catheter system, the study aims to make this minimally invasive procedure safer and more accessible, particularly for younger patients who may face complications from long-term anticoagulation therapy. The approach involves advanced 3D visualization techniques to improve the precision of the procedure, ultimately aiming to reduce the risk of blood clots and strokes. Patients will be monitored throughout the process to assess the effectiveness and safety of this innovative technique.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients with non-valvular atrial fibrillation, particularly younger individuals with a long life expectancy who are at risk for bleeding complications.

Not a fit: Patients with valvular atrial fibrillation or those who are not candidates for catheter-based procedures may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a safer and more effective alternative to long-term anticoagulation therapy for patients at risk of stroke due to atrial fibrillation.

How similar studies have performed: Previous research has shown promising results with similar minimally invasive techniques for stroke prevention, indicating potential for success in this novel approach.

Where this research is happening

Cleveland, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.