NIH-funded research NIH-funded research

Using acupuncture to manage pain in sickle cell disease

Official title: Integrative Medicine for Pain Management in Sickle Cell Disease

Funded at Indiana University Indianapolis · NIH-10683217 · Data updated 2026-11-12

This study is looking at how acupuncture can help people with sickle cell disease manage their chronic pain without using medication, and it aims to find out why some people respond better to this treatment than others, so we can create better pain relief options for everyone.

More Sickle Cell Disease research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionIndiana University Indianapolis
NIH-funded
Lab location1 site (Indianapolis, United States)
Project startJuly 17, 2018
Project endAugust 31, 2025
Funding year2023
Award (this year)$240,872
NIH project number5R00AT010012-05
Project IDNIH-10683217 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with sickle cell disease who experience chronic pain.

Less likely to help

Patients who do not have sickle cell disease or those who do not experience chronic pain may not benefit from this research.

What this research studies

This research investigates the effectiveness of acupuncture as a non-drug therapy for managing chronic pain in patients with sickle cell disease. It aims to understand how specific inflammatory biomarkers affect the pain relief provided by acupuncture and to identify the mechanisms behind varying responses to this treatment. By studying both animal models and human patients, the research seeks to establish a systematic approach to enhance pain management strategies for those who do not respond well to traditional therapies. The findings could lead to more personalized and effective pain relief options for patients suffering from this condition.

Why it matters

Potential benefit: If successful, this research could provide a safer and more effective pain management option for patients with sickle cell disease, reducing reliance on opioids.

How similar studies have gone: Previous studies have shown promising results for acupuncture in pain management, but this research aims to provide more definitive evidence and understanding of its mechanisms in sickle cell disease.

Where this research is happening

  • Indiana University Indianapolis
    Indianapolis, United States
    Active

Researchers

  • Principal investigator: Wang, Ying — Indiana University Indianapolis
  • Study coordinator: Wang, Ying

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.