Using Acomys to explore genetic tools for regeneration
Official title: Establishing Acomys as a genetic platform for regeneration research
Funded at Seattle Children's Hospital · NIH-10866878 · Data updated 2026-11-12
This study is exploring a special type of rodent that can regrow body parts to help scientists learn more about how regeneration works, which could lead to better treatments for healing and aging-related issues in people.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Seattle Children's Hospital NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | July 1, 2024 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $293,550 |
| NIH project number | 1R21OD036471-01 |
| Project ID | NIH-10866878 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals aged 65 and older who may benefit from advancements in regenerative therapies.
✕Less likely to help
Patients with conditions that do not involve regenerative challenges or those who are not within the targeted age group may not receive benefits from this research.
What this research studies
This research focuses on developing Acomys, a unique rodent species known for its remarkable regenerative abilities, as a new genetic platform for studying regeneration. By utilizing advanced sequencing technologies, the project aims to create genetic tools that can help researchers better understand the mechanisms behind regeneration in mammals. This could lead to significant advancements in regenerative medicine, particularly for conditions related to aging and tissue repair. The research will involve laboratory maintenance of Acomys and the development of methodologies to manipulate their genetic traits.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in regenerative medicine, offering new treatments for patients with injuries or degenerative diseases.
How similar studies have gone: Other research has shown success in using unique model organisms for significant biological discoveries, indicating a promising potential for this novel approach.
Where this research is happening
-
Seattle Children's Hospital
Seattle, United States Active
Researchers
- Principal investigator: Millen, Kathleen Joyce — Seattle Children's Hospital
- Study coordinator: Millen, Kathleen Joyce
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.