Using a very low-carbohydrate diet to lower diabetes risk

Testing a very low-carbohydrate diet version of the Diabetes Prevention Program to reduce risk factors for type 2 diabetes

['FUNDING_R01'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-11085174

This study is looking at whether a very low-carb diet can help people at risk for type 2 diabetes do better in a program designed to prevent the disease, and it’s for adults who want to improve their blood sugar levels and overall health.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded)
Locations1 site (ANN ARBOR, UNITED STATES)
Trial IDNIH-11085174 on ClinicalTrials.gov

What this research studies

This research investigates how a very low-carbohydrate diet can improve the effectiveness of the Diabetes Prevention Program (DPP) in reducing the risk of developing type 2 diabetes. Participants will be involved in a randomized controlled trial where they will follow this dietary approach, which is believed to better manage blood sugar levels compared to traditional low-fat diets. The study aims to assess the acceptability and feasibility of this dietary strategy among adults at risk for diabetes, focusing on weight loss and metabolic health improvements.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who are at risk for type 2 diabetes, particularly those with prediabetes or obesity.

Not a fit: Patients who are not at risk for type 2 diabetes or those with established diabetes may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a more effective dietary intervention for preventing type 2 diabetes in at-risk adults.

How similar studies have performed: Previous research has shown that dietary interventions can significantly impact diabetes prevention, but this specific approach using a very low-carbohydrate diet is relatively novel.

Where this research is happening

ANN ARBOR, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: adult onset diabetes, Adult-Onset Diabetes Mellitus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.